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  2. T-cell depletion - Wikipedia

    en.wikipedia.org/wiki/T-cell_depletion

    T-cell depletion (TCD) is the process of T cell removal or reduction, which alters the immune system and its responses. ... In allogeneic bone marrow transplants (BMT ...

  3. Anti-thymocyte globulin - Wikipedia

    en.wikipedia.org/wiki/Anti-thymocyte_globulin

    Anti-thymocyte globulin (ATG) is an infusion of horse or rabbit-derived antibodies against human T cells and their precursors , which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia due to bone marrow insufficiency.

  4. T cell deficiency - Wikipedia

    en.wikipedia.org/wiki/T_cell_deficiency

    T cell deficiency is a deficiency of T cells, caused by decreased function of individual T cells, it causes an immunodeficiency of cell-mediated immunity. [1] T cells normal function is to help with the human body's immunity, they are one of the two primary types of lymphocytes (the other being B cells ).

  5. Thymoglobulin - Wikipedia

    en.wikipedia.org/wiki/Thymoglobulin

    While these antibodies have a variety of specificities, their main mechanism of immunosuppression is through depletion of T cells. Thymoglobulin is currently approved for clinical use in Europe and the United States for renal allograft rejection, prevention of graft-vs.-host disease, and conditions involving bone marrow failure, including ...

  6. Graft-versus-host disease - Wikipedia

    en.wikipedia.org/wiki/Graft-versus-host_disease

    GvHD is commonly associated with bone marrow transplants and stem cell transplants. White blood cells of the donor's immune system which remain within the donated tissue (the graft) recognize the recipient (the host) as foreign (non-self). The white blood cells present within the transplanted tissue then attack the recipient's body's cells ...

  7. 65 Unsettling Medical Facts That Are Not For The Faint Of Heart

    www.aol.com/lifestyle/65-unsettling-medical...

    A lot of those transplants don't "take." And even if they do, the body can revert back to its old microbiome (and associated conditions) due to the recipient's diet and location.

  8. T cell - Wikipedia

    en.wikipedia.org/wiki/T_cell

    T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, [1] found in the bone marrow.

  9. Bone marrow failure - Wikipedia

    en.wikipedia.org/wiki/Bone_marrow_failure

    Inherited bone marrow failure syndromes may require hematopoietic stem cell transplantation. Depending on severity, aplastic anemia may be treated with T-cell suppression in the form of cyclosporine and anti-thymocyte globulin, or may require hematopoietic stem cell transplantation.

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