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Rare but potentially critical complications are cardiac arrest, abnormal heart rhythms, severe low blood pressure, seizures, and neuroleptic malignant syndrome. [12] Life-threatening overdose is rare, [ 12 ] however, as the median lethal dose is about 338 milligrams/kilogram in mice and 425 mg/kg in rats. [ 12 ]
For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that a reduction of blood pressure by 5 mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%.
An antihypotensive, also known as vasopressor, is an agent that raises blood pressure by constricting blood vessels, thereby increasing systemic vascular resistance. This is different from inotropes which increase the force of cardiac contraction. Some substances do both (e.g. dopamine, dobutamine).
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. [11] High blood pressure usually does not cause symptoms itself. [1]
The units for the Heart Rate are beats per minute and for the Blood Pressure mmHg. Rate pressure product is a measure of the stress put on the cardiac muscle based on the number of times it needs to beat per minute (HR) and the arterial blood pressure that it is pumping against (SBP). It will be a direct indication of the energy demand of the ...
"Your blood pressure is supposed to be under 140 over 90, optimally closer to 120 over 80."
Raises blood pressure and heart rate. [2] Sexual stimulation; Male erectile dysfunction; Hypotension [2] May cause anxiety [12] Central Nervous System stimulation; Labetalol: Trandate Blocks some α 1 receptor activity, but binds more strongly to β receptors. [2] Lowers blood pressure, increases heart rate slightly. [2] Hypertension [2] [13 ...
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