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  2. Cyclobenzaprine - Wikipedia

    en.wikipedia.org/wiki/Cyclobenzaprine

    Rare but potentially critical complications are cardiac arrest, abnormal heart rhythms, severe low blood pressure, seizures, and neuroleptic malignant syndrome. [12] Life-threatening overdose is rare, [ 12 ] however, as the median lethal dose is about 338 milligrams/kilogram in mice and 425 mg/kg in rats. [ 12 ]

  3. Antihypotensive - Wikipedia

    en.wikipedia.org/wiki/Antihypotensive

    An antihypotensive, also known as vasopressor, is an agent that raises blood pressure by constricting blood vessels, thereby increasing systemic vascular resistance. This is different from inotropes which increase the force of cardiac contraction. Some substances do both (e.g. dopamine, dobutamine).

  4. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that a reduction of blood pressure by 5 mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%.

  5. Management of hypertension - Wikipedia

    en.wikipedia.org/wiki/Management_of_hypertension

    For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]

  6. Muscarinic antagonist - Wikipedia

    en.wikipedia.org/wiki/Muscarinic_antagonist

    It [clarification needed] has an opposite effect on blood pressure. Tachycardia and stimulation of the vasomotor center causes an increase in blood pressure. But, due to feedback regulation of the vasomotor center, there is a fall in blood pressure due to vasodilation.

  7. Alpha blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha_blocker

    Raises blood pressure and heart rate. [2] Sexual stimulation; Male erectile dysfunction; Hypotension [2] May cause anxiety [12] Central Nervous System stimulation; Labetalol: Trandate Blocks some α 1 receptor activity, but binds more strongly to β receptors. [2] Lowers blood pressure, increases heart rate slightly. [2] Hypertension [2] [13 ...

  8. Labile hypertension - Wikipedia

    en.wikipedia.org/wiki/Labile_hypertension

    Typically, an increase in blood pressure may put strain on the heart and possibly other organs that may cause damage to the blood vessels, eyes and the heart. Uncontrollable increase in blood pressure can cause damage to the arteries that are present around kidneys, and thus restrict the blood to deliver. Due to inconsistent fluctuations in ...

  9. Serotonin–dopamine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin–dopamine...

    Medifoxamine (Cledial, Gerdaxyl) is an antidepressant that appears to act as an SDRI as well as a 5-HT 2 receptor antagonist. [3] Sibutramine (Reductil, Meridia, Siredia, Sibutrex) is a withdrawn anorectic that itself as a molecule in vitro is an SNDRI but preferentially an SDRI, with 18.3- and 5.8-fold preference for inhibiting the reuptake of serotonin and dopamine over norepinephrine ...

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