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UPSIT has been used to detect Alzheimer's (AD). Smell loss can be a very early sign of detecting AD. [21] It has been suggested that AD affects odor identification and odor detection, this shows that AD patients have more trouble performing higher olfactory tasks that involve specific cognitive processes.
One of APOPO's "HeroRATs" in Cambodia. APOPO (Dutch: Anti-Persoonsmijnen Ontmijnende Product Ontwikkeling, lit. 'Anti-Personnel Landmines Detection Product Development' [1]) is a registered Belgian non-governmental organisation and US non-profit which trains southern giant pouched rats [1] and technical survey dogs to detect landmines and tuberculosis. [2]
A HeroRAT being rewarded with a banana Cricetomys gambianus is a species of giant pouched rat.. Magawa (November 2013 – January 2022) was an African giant pouched rat (Cricetomys ansorgei) that worked as a HeroRAT sniffing out landmines in Cambodia for the non-governmental organization APOPO (in English, Anti-Personnel Landmines Removal Product Development) which trains rats to detect ...
Smell as evidence of disease has been long used, dating back to Hippocrates around 400 years BCE. [1] It is still employed with a focus on volatile organic compounds (VOCs) found in body odor. [ 2 ] VOCs are carbon-based molecular groups having a low molecular weight, secreted during cells' metabolic processes. [ 3 ]
In the U.S., the numbers of rats and mice used are not reported, but estimates range from around 11 million [3] to approximately 100 million. [4] In 2000, the Federal Research Division, Library of Congress, published the results of an analysis of its Rats/Mice/and Birds Database: Researchers, Breeders, Transporters, and Exhibitors.
Age is the strongest reason for olfactory decline in healthy adults, having even greater impact than does cigarette smoking. Age-related changes in smell function often go unnoticed and smell ability is rarely tested clinically unlike hearing and vision. 2% of people under 65 years of age have chronic smelling problems.
Bedding maintenance is an important part of both human and animal health, cleanliness, and well being. [3] Storage of bedding is important to insure that the bedding does not ruin. The best place to store it is in an environment that is dry and above ground level. Frequent bedding change is important to decrease the amount of bacteria. [3]
The leading cause to the loss of smell is URTI, Smell loss in URTI is caused by a multifactorial combination of mechanical obstruction for the odorant transmission in the olfactory cleft due to mucosal inflammation (cytokine storm) and shedding (neurodegeneration) of the olfactory neuro-epithelium which interfere with odorants binding to OR [19]