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Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative.It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects.
Benadryl Dry, Tickly Cough Liquid is a cough medicine found in Australia. It is used to temporarily relieve irritating coughs. Pholcodine is the main ingredient found in this cough liquid. [11] This medication is to be taken orally and may cause drowsiness. In India, Benadryl can also be found in the form of a cough liquid and also cough lozenges.
As with dimenhydrinate, the stimulant effect of the etanautine counteracts the sedative effect from the diphenhydramine, resulting in an improved therapeutic profile. [2] The 1:2 salt diphenhydramine diacefylline (with two molecules of acefylline to each molecule of diphenhydramine) is also used in medicine, under the brand name Nautamine. [1] [3]
In July 1975, the J. B. Williams Co. began marketing Sominex 2. [37] On November 24, 1975, Attorney General Evelle J. Younger filed suit on behalf of the State of California against Williams Co., stating that the product did not warn against use by pregnant or nursing women or persons with asthma or COPD, nor did it notify consumers that it should not be used in conjunction with alcohol. [38]
Medications in the recall included liquid versions of Tylenol, Tylenol Plus, Motrin, Zyrtec, and Benadryl. The products were recalled after it was determined that they "may not fully meet the required manufacturing specifications". [1] [2] The recall affected at least 12 countries. [1]
The active ingredients usually belong to these classes: Antihistamines such as diphenhydramine (Benadryl) and hydroxyzine; Corticosteroids such as hydrocortisone topical cream, see topical steroid; Counterirritants, such as mint oil, menthol, or camphor [9] Local anesthetics such as lidocaine, pramoxine, or benzocaine in topical creams or lotions
The flagship cough syrup and cold care brand is marketed in several countries as Benylin DM, for its active ingredient, dextromethorphan. However, the range of products available in both solid dosage and liquid forms have formulations with multiple ingredients including pseudoephedrine, paracetamol (acetaminophen) and guaifenesin.
It is available as an over-the-counter medicine in the UK, and is available with or without pseudoephedrine under the Benadryl brand. In the U.S., acrivastine was the active ingredient in Semprex-D. Semprex-D also contains the decongestant pseudoephedrine. Semprex-D was marketed in the U.S. by Actient Pharmaceuticals.