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Mycophenolate mofetil, a prodrug form of mycophenolic acid used in medicine. Mycophenolate mofetil is the morpholino ethyl ester of mycophenolic acid; the ester masks the carboxyl group. [42] Mycophenolate mofetil is reported to have a pKa values of 5.6 for the morpholino moiety and 8.5 for the phenolic group.
pentoxyfylline – xanthine derivative used in as an antiinflammatory drug and in the prevention of endotoxemia; pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID)
Since untreated feline infectious peritonitis (FIP) is fatal in almost all cases [9] and in most countries there are no approved treatments available, GS-441524 has reportedly been sold illegally worldwide on the black market and used by pet owners to treat affected cats, although Gilead Sciences has refused to license the drug for veterinary use.
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Researchers are engineering a parasite that spreads through cat feces to deliver therapeutic drugs to the brain. This is because the parasite is able to cross the blood-brain barrier, an important ...
The four toxicity categories, from one to four are: Toxicity category I is highly toxic and severely irritating, Toxicity category II is moderately toxic and moderately irritating,
They wanted to see if the drugs had similar effects on the monkeys. The results showed that cocaine and some of the other drugs had similar effects in maintaining the monkeys' self-administration behavior. However, one of the drugs, mazindol, didn't have the same effect on all the monkeys.
The US Food and Drug Administration (FDA) approved it for flea treatment in dogs in May 2014, [17] and approved the combination fluralaner/moxidectin (Bravecto Plus) as a topical treatment for cats in November 2019.
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