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Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
Patients with narcolepsy are diagnosed as either type 1 or type 2, with only the former presenting cataplexy symptoms. [57] Type 1 narcolepsy results from the loss of approximately 70,000 orexin -releasing neurons in the lateral hypothalamus , leading to significantly reduced cerebrospinal orexin levels; [ 58 ] [ 59 ] this reduction is a ...
Narcolepsy with cataplexy is considered an autoimmune-mediated disorder, so some therapies based on this hypothesis have been developed. Immunological therapies developed include: [ 20 ] Corticosteroids : after testing in 1 human and 1 canine case it proved to be ineffective so is less likely to be further used.
3. Limit non-sleep activities. From our phones, friends, and work, to our favorite Netflix shows, we receive a lot of stimulation during the day.
A drunken police officer in Zambia freed 13 suspects from custody so that they could go and celebrate the new year, officials say. Detective inspector Titus Phiri was arrested after releasing the ...
Walmart and Branch Messenger, a payments platform, accused of deceiving workers about pay from retailer for two years.
Banjo fittings are commonly found in automotive fuel, [2] motor oil and hydraulic systems (e.g.: brakes and clutch).General applications include: Hydraulic power systems; Power steering fluid
Israeli Prime Minister Benjamin Netanyahu on Sunday said that the collapse of Bashar al-Assad’s regime in Syria was a “direct result” of Israel’s military campaign against Iran and its ...
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