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2. Celecoxib - Wikipedia

   en.wikipedia.org/wiki/Celecoxib

   Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. [7]

3. Valdecoxib - Wikipedia

   en.wikipedia.org/wiki/Valdecoxib

   Other reported side effects were angina and Stevens–Johnson syndrome. Pfizer first acknowledged cardiovascular risks associated with Bextra in October 2004. The American Heart Association soon after was presented with a report indicating patients using Bextra while recovering from heart surgery were 2.19 times more likely to suffer a stroke ...

4. Discovery and development of cyclooxygenase 2 inhibitors

   en.wikipedia.org/wiki/Discovery_and_development...

   The impetus for development of selective COX-2 inhibitors was the adverse gastrointestinal side-effects of NSAIDs.Soon after the discovery of the mechanism of action of NSAIDs, strong indications emerged for alternative forms of COX, but little supporting evidence was found.

5. Say goodbye to pain with these smart patches - AOL

   www.aol.com/lifestyle/goodbye-pain-smart-patches...

   Kailo is a reusable pain patch that uses your body’s electrical signals to relieve physical pain. The patches are waterproof and flexible, so stick the adhesive near the inflamed area and go ...

6. How nitric oxide supplements can enhance your sex life - AOL

   www.aol.com/nitric-oxide-supplements-enhance-sex...

   And while most side effects can be described as mild-to-moderate, nitric oxide supplements can also pose a risk for more serious side effects in people with certain health conditions, such as ...

7. Combined hormonal contraception - Wikipedia

   en.wikipedia.org/wiki/Combined_hormonal...

   The most common side-effects of combined hormonal contraceptives include headache, nausea, breast tenderness, and breakthrough bleeding. Vaginal ring use can include additional side-effects including vaginal irritation and vaginal discharge. Contraceptive skin patch use can also include a side-effect of skin irritation around the patch site. [39]

8. Rofecoxib - Wikipedia

   en.wikipedia.org/wiki/Rofecoxib

   The therapeutic recommended dosages were 12.5, 25, and 50 mg with an approximate bioavailability of 93%. [12] [13] [14] Rofecoxib crossed the placenta and blood–brain barrier, [12] [13] [15] and took 1–3 hours to reach peak plasma concentration with an effective half-life (based on steady-state levels) around 17 hours.

9. Nancy Pelosi undergoes hip replacement surgery after fall in ...

   www.aol.com/nancy-pelosi-hospitalized-during...

   Democratic Rep. Nancy Pelosi, 84, underwent a successful hip replacement surgery after falling while in Luxembourg with a congressional delegation, her office said Saturday. "Earlier this morning ...