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The Na + /K +-ATPase, as well as effects of diffusion of the involved ions, are major mechanisms to maintain the resting potential across the membranes of animal cells.. The relatively static membrane potential of quiescent cells is called the resting membrane potential (or resting voltage), as opposed to the specific dynamic electrochemical phenomena called action potential and graded ...
In the pacemaking cells of the heart (e.g., the sinoatrial node), the pacemaker potential (also called the pacemaker current) is the slow, positive increase in voltage across the cell's membrane, that occurs between the end of one action potential and the beginning of the next.
Cell excitability is the change in membrane potential that is necessary for cellular responses in various tissues. Cell excitability is a property that is induced during early embriogenesis. [26] Excitability of a cell has also been defined as the ease with which a response may be triggered. [27]
A current–voltage characteristic or I–V curve (current–voltage curve) is a relationship, typically represented as a chart or graph, between the electric current through a circuit, device, or material, and the corresponding voltage, or potential difference, across it.
If the injected current were used as a bifurcation parameter, then the Hodgkin–Huxley model undergoes a Hopf bifurcation. As with most neuronal models, increasing the injected current will increase the firing rate of the neuron. One consequence of the Hopf bifurcation is that there is a minimum firing rate.
A problem arises because the electrode is between the amplifier and the cell; i.e., the electrode is in series with the resistor that is the cell's membrane. Thus, when passing current through the electrode and the cell, Ohm's law tells us that this will cause a voltage to form across both the cell's and the electrode's resistance. As these ...
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A channel that is "inwardly-rectifying" is one that passes current (positive charge) more easily in the inward direction (into the cell) than in the outward direction (out of the cell). It is thought that this current may play an important role in regulating neuronal activity, by helping to stabilize the resting membrane potential of the cell.