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The bladder also contains β 3 adrenergic receptors, and pharmacological agonists of this receptor are used to treat overactive bladder. The mucosa of the urinary bladder may herniate through the detrusor muscle. [6] This is most often an acquired condition due to high pressure in the urinary bladder, damage, or existing connective tissue ...
The bladder wall muscle overactivity results in sporadic bladder muscle contraction, which increases pressure in the bladder and decreases the volume of urine the bladder can hold. [2] If NDO is not treated, increased pressure in the bladder can put the upper urinary tract at risk of harm, including possible permanent damage to the kidneys. [ 2 ]
Chronic urinary retention that is due to bladder blockage which can either be as a result of muscle damage or neurological damage. [7] If the retention is due to neurological damage, there is a disconnect between the brain to muscle communication, which can make it impossible to completely empty the bladder. [ 7 ]
Berberine can upset your gastrointestinal system, causing symptoms like: nausea, diarrhea, constipation, gas and abdominal pain, Simmons says. It’s also possible that taking berberine can ...
Trospium chloride is a muscarinic antagonist used to treat overactive bladder. [3] It has side effects typical of this class of drugs, namely dry mouth, stomach upset, and constipation; these side effects cause problems with people taking their medicine as directed.
In cases where the bladder is spasming uncontrollably, Botox injections can help calm that muscle, Dr. Linehan says. (Here are 10 things you should know about botox injections .) Nerve stimulation
The results aren't all that surprising; Botox is already approved as a treatment for overactive bladder associated with a neurological condition like a spinal cord injury or multiple sclerosis or ...
Urine storage and elimination (urination) requires coordination between the bladder emptying muscle (detrusor) and the external sphincter of the bladder. This coordination can be disrupted by damage or diseases of the central nervous system, peripheral nerves or autonomic nervous system. [8]