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Mitochondrial replacement therapy (MRT), sometimes called mitochondrial donation, is the replacement of mitochondria in one or more cells to prevent or ameliorate disease. MRT originated as a special form of in vitro fertilisation in which some or all of the future baby's mitochondrial DNA (mtDNA) comes from a third party.
An IVF technique known as mitochondrial donation or mitochondrial replacement therapy (MRT) results in offspring containing mtDNA from a donor female, and nuclear DNA from the mother and father. In the spindle transfer procedure, the nucleus of an egg is inserted into the cytoplasm of an egg from a donor female which has had its nucleus removed ...
A third party's mitochondrial DNA is transferred to the future mother's ovum. This is used to prevent mitochondrial disease. Embryo donation. with embryos which were originally created for a genetic mother's assisted pregnancy. Once the genetic mother has completed her own treatment, she may donate unused embryos for use by a third party.
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