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Adjuvant therapy, also known as adjunct therapy, adjuvant care, or augmentation therapy, is a therapy that is given in addition to the primary or initial therapy to maximize its effectiveness. The surgeries and complex treatment regimens used in cancer therapy have led the term to be used mainly to describe adjuvant cancer treatments.
Common side effects include fever, infection, cough, headache, trouble sleeping, and rash. [31] Other severe side effects include heart failure, allergic reactions, and lung disease. [31] Use during pregnancy may harm the baby. [23] Trastuzumab works by binding to the HER2 receptor and slowing down cell replication. [31]
Type I inducers cause stress to the ER only as collateral damage, mainly targeting DNA or chromatin maintenance apparatus or membrane components. Type II inducers target the ER specifically. [ 3 ] ICD is induced by some cytostatic agents such as anthracyclines , [ 4 ] oxaliplatin and bortezomib , or radiotherapy and photodynamic therapy (PDT ...
A major drawback of ipilimumab therapy is its association with severe and potentially fatal immunological adverse effects due to T cell activation and proliferation, occurring in ten to twenty percent of patients. [33] Serious adverse effects include stomach pain, bloating, constipation, diarrhea, fever, trouble breathing, and urinating problems.
The word "adjuvant" comes from the Latin word adiuvare, meaning to help or aid. "An immunologic adjuvant is defined as any substance that acts to accelerate, prolong, or enhance antigen-specific immune responses when used in combination with specific vaccine antigens." [2]
Dense breasts are extremely common, and women are already being notified if they have them—now they need to be able to do something about it. It's critical that we: Ensure women are aware of ...
Vagus nerve stimulation therapy improved the symptoms of treatment-resistant depression for nearly 500 participants in a major clinical trial.
Trastuzumab deruxtecan is indicated for the treatment of adults with unresectable (unable to be removed with surgery) or metastatic (when cancer cells spread to other parts of the body) HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting and for adults with locally advanced or metastatic HER2-positive gastric or gastroesophageal ...