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A Necator americanus larva. Helminthic therapy, an experimental type of immunotherapy, is the treatment of autoimmune diseases and immune disorders by means of deliberate infestation with a helminth or with the eggs of a helminth. [1]
Some types of helminths and protozoa are classified as intestinal parasites that cause infection—those that reside in the intestines. These infections can damage or sicken the host (humans or other animals). If the intestinal parasite infection is caused by helminths, the infection is called helminthiasis.
A 2008 study found that about 40% of Hong Kong children with autism spectrum disorder were treated with CAM, with the most popular therapies being acupuncture, sensory integration therapy, and Chinese herbology; the 40% is a lower prevalence than in Canada and the U.S., where biological-based therapies such as special diets predominate. [7]
Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals, particularly small ruminants such as goats and sheep. [1] Anthelmintic medication is also used in mass deworming campaigns of school-aged children in many developing countries.
Over 270 million preschool-age children and over 600 million school-age children live in areas where these parasites are intensively transmitted, and need treatment and preventive interventions. Latest estimates indicate that more than 880 million children need treatment from STH infections. [3] [18] [31] By type of parasitic worm, the ...
Furthermore, children with the highest counts of blood flukes also had the most malaria attacks. [25] Based on this study, Hartgers et al. drew a "cautious conclusion" that helminths make humans more susceptible to contracting malaria and experiencing some of its lighter symptoms, while actually protecting them from the worst symptoms. [26]
These "ropeworms" are often discussed, with images shared and claimed as evidence of successful detoxing, on autism forums and altmed Facebook groups, wherein various toxic and/or ineffective products are falsely claimed to cure autism and a myriad of other conditions and ailments. [7]
It is well established that T helper 2 cells are the central players of protective immunity to helminths, [12] while the roles for B cells and antibodies are context-dependent. [13] Inflammation leads to encapsulation of egg deposits throughout the body. Helminths excrete into the intestine toxic substances after they feed.
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