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The oral bioavailability of amphetamine varies with gastrointestinal pH; [20] it is well absorbed from the gut, and bioavailability is typically 90%. [10] Amphetamine is a weak base with a p K a of 9.9; [ 189 ] consequently, when the pH is basic, more of the drug is in its lipid soluble free base form, and more is absorbed through the lipid ...
In the lab, phenyl-2-nitropropene is produced by the reaction of benzaldehyde and nitroethane in the presence of a basic catalyst like n-butylamine.The reaction is a nitroaldol reaction, and is a variant of a Knoevenagel condensation reaction, which is one of a broader class of reactions called Henry condensations, or simply Henry reactions.
Levoamphetamine [note 1] is a stimulant medication which is used in the treatment of certain medical conditions. [10] It was previously marketed by itself under the brand name Cydril, but is now available only in combination with dextroamphetamine in varying ratios under brand names like Adderall and Evekeo.
The GNC Pro Performance Grip Gauntlet debuted at the 2004 Arnold Expo Challenge. The three implements used were the No. 3 Captains of Crush gripper, the York Blob and the Rolling Thunder. [ 1 ] An estimated 20,000 competitors at Fitness Expos over a 7-year run from 2004 to 2010 tested their hands at the GNC Grip Gauntlet.
On 20 June 2014, Shire rejected a takeover attempt by AbbVie. AbbVie offered £46.11 per share (£27.3 billion or $46.5 billion in total). [30] On 8 July, the offer was increased to $51.5 billion. [31] On 18 July, it was announced that AbbVie would acquire Shire for $54.8 billion. [32]
Amphetamine [note 2] (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine.
GNC Holdings, LLC (an initialism of General Nutrition Centers) is an American multinational retail and nutritional manufacturing company based in Pittsburgh, Pennsylvania. [5] [6] It specializes in health and nutrition related products, including vitamins, supplements, minerals, herbs, sports nutrition, diet, and energy products.
[20] Methylphenidate – a benzylpiperidine derivative that may improve working memory, episodic memory, and inhibitory control, aspects of attention, and planning latency in healthy people. [13] [15] It also may improve task saliency and performance on tedious tasks. [17]
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261