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The oral bioavailability of amphetamine varies with gastrointestinal pH; [20] it is well absorbed from the gut, and bioavailability is typically 90%. [10] Amphetamine is a weak base with a p K a of 9.9; [ 189 ] consequently, when the pH is basic, more of the drug is in its lipid soluble free base form, and more is absorbed through the lipid ...
The first six characters of the GPI define the therapeutic class code, the next two pairs the drug name, and the last four define route, dosage or strength. For example GPI 58-20-00-60-10-01-05 is for the drug nortriptyline HCl cap 10 mg (an antidepressant) and can be further classified as follows: [1]
The allegations included claims that Shire had made exaggerated and false statements regarding product safety, promoted medications for non-FDA approved off-label use, and marketed products on unsubstantiated claims of beneficial side effects, including reductions in criminality, traffic accidents, sexually transmitted infections, and divorce ...
Levoamphetamine [note 1] is a stimulant medication which is used in the treatment of certain medical conditions. [10] It was previously marketed by itself under the brand name Cydril, but is now available only in combination with dextroamphetamine in varying ratios under brand names like Adderall and Evekeo.
In the lab, phenyl-2-nitropropene is produced by the reaction of benzaldehyde and nitroethane in the presence of a basic catalyst like n-butylamine.The reaction is a nitroaldol reaction, and is a variant of a Knoevenagel condensation reaction, which is one of a broader class of reactions called Henry condensations, or simply Henry reactions.
GNC Holdings, LLC (an initialism of General Nutrition Centers) is an American multinational retail and nutritional manufacturing company based in Pittsburgh, Pennsylvania. [5] [6] It specializes in health and nutrition related products, including vitamins, supplements, minerals, herbs, sports nutrition, diet, and energy products.
Indicated for exogenous obesity, [3] between 1965 and 1973, Obetrol was marketed in 10 mg and 20 mg strength through Obetrol Pharmaceuticals division of the American pharmaceutical company Rexar. When sold directly to physicians, Obetrol used the brand name Oby-Rex .
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.