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Carbohydrazide is the chemical compound with the formula OC(N 2 H 3) 2. It appears as a white solid that is soluble in water, [ 1 ] [ 2 ] but not in many organic solvents, such as ethanol, ether or benzene.
The tables below provides information on the variation of solubility of different substances (mostly inorganic compounds) in water with temperature, at one atmosphere pressure. Units of solubility are given in grams of substance per 100 millilitres of water (g/(100 mL)), unless shown otherwise. The substances are listed in alphabetical order.
An applied example is a synthesis of sunitinib begins by mixing 5-fluoroisatin slowly into hydrazine hydrate. [10] After 4 hours at 110 °C, the indole ring structure has been broken into (2-amino-5-fluoro-phenyl)-acetic acid hydrazide with reduction of the ketone at the 3-position.
The following chart shows the solubility of various ionic compounds in water at 1 atm pressure and room temperature (approx. 25 °C, 298.15 K). "Soluble" means the ionic compound doesn't precipitate, while "slightly soluble" and "insoluble" mean that a solid will precipitate; "slightly soluble" compounds like calcium sulfate may require heat to precipitate.
Aromatic monosubstituted and asymmetrically disubstituted hydrazines are poorly soluble in water, less basic and weaker reducing agents. For the preparation of aliphatic hydrazines, the reaction of hydrazine with alkylating compounds such as alkyl halides is used, or by reduction of nitroso derivatives.
It is a water-soluble white solid. It is a derivative of urea. ... A further reaction can occur to give carbohydrazide: OC(NH 2)(N 2 H 3) + N 2 H 4 → OC(N 2 H 3) 2 ...
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The following compounds are liquid at room temperature and are completely miscible with water; they are often used as solvents. Many of them are hygroscopic.