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A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. [ 1 ] [ 2 ] Drug therapy ( pharmacotherapy ) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for ...
The monoamine hypothesis was originally proposed based on observations that reserpine, a drug which depletes the monoamine neurotransmitters, produced depressive effects in people, [201] and that certain hydrazine antituberculosis agents like iproniazid, which prevent the breakdown of monoamine neurotransmitters, produced apparent ...
Isotretinoin is the only non-psychiatric drug on the FDA's top 10 list of drugs associated with depression [57] [62] and is also within the top 10 for suicide attempts. [63] A black box warning for suicide, depression, and psychosis has been present on isotretinoin's packaging in the United States since 2005. [ 62 ]
Placebo-controlled trials of both first- and second-generation antipsychotic drugs consistently demonstrate the superiority of active drugs over placebos in suppressing psychotic symptoms. [25] A large meta-analysis of 38 trials of antipsychotic drugs in schizophrenia with acute psychotic episodes showed an effect size of about 0.5. [ 37 ]
The original SPR used an early PRI flip-up front sight with an elevation dial, which has since been discontinued. The Mk 12 MOD 0/H uses the current PRI flip-up front sight. The SPR/A, SPR/B, and Mk 12 MOD 1 use the KAC rail forend flip-up front sight, KAC part number 99051. The SPR and Mk 12 MOD 0/H use the ARMS #40 flip up rear sight.
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