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The first pharyngeal arch, also mandibular arch (corresponding to the first branchial arch of fish), is the first of six pharyngeal arches that develops during the fourth week of development. [10] It is located between the stomodeum and the first pharyngeal groove .
The first and second arches disappear early. A remnant of the 1st arch forms part of the maxillary artery, [3] a branch of the external carotid artery. The ventral end of the second develops into the ascending pharyngeal artery, and its dorsal end gives origin to the stapedial artery, [3] a vessel which typically atrophies in humans [4] [5] but persists in some mammals.
Pattern of the pharyngeal arches. I-IV pharyngeal arches, 1–4 pharyngeal pouches (inside) and/or pharyngeal grooves (outside) a Tuberculum laterale b Tuberculum impar c Foramen cecum d Ductus thyreoglossus e Sinus cervicalis. The pharyngeal apparatus is an embryological structure. [1] [2] It consists of: pharyngeal grooves (from ectoderm ...
In the fourth week of the pregnancy the structures that develop the tongue appear. These structures develop from the first pharyngeal arch are two lingual lateral prominences and one in the middle that does not develop and disappears. A second prominence, the hypobranchial eminence, comes from the second, third and fourth pharyngeal arches. A ...
Derivatives include: superior parathyroid glands and ultimobranchial body which forms the parafollicular C-Cells of the thyroid gland. Musculature and cartilage of larynx (along with the sixth pharyngeal arch). Nerve supplying these derivatives is Superior laryngeal nerve.
Parafollicular cells are derived from pharyngeal endoderm. [2] [3] Embryologically, they associate with the ultimopharyngeal body, which is a ventral derivative of the fourth (or fifth) pharyngeal pouch. Parafollicular cells were previously believed to be derived from the neural crest based on a series of experiments in quail-chick chimeras.
Pattern of the pharyngeal arches. I-IV pharyngeal arches, 1-4 pharyngeal pouches (inside) and/or pharyngeal grooves (outside) a Lateral lingual swellings b Median tongue bud c Foramen cecum d Thyroglossal duct e Cervical sinus. The median tongue bud (also tuberculum impar) marks the beginning of the development of the tongue.
Cells found in the fourth aortic arch differentiates to form the distal aortic arch and right subclavian artery, whilst cells in the sixth aortic arch develops into the pulmonary arteries. Cardiac neural crest cells express Hox genes that supports the development of arteries 3, 4 and 6 and the simultaneous regression of arteries 1 and 2.