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Brugada syndrome (BrS) is a genetic disorder in which the electrical activity of the heart is abnormal due to channelopathy. [2] It increases the risk of abnormal ...
Long QT syndrome, the most common form of cardiac channelopathy, is characterized by prolonged ventricular repolarization, predisposing to a high risk of ventricular tachyarrhythmias (e.g., torsade de pointes), syncope, and sudden cardiac death.
Long QT syndrome is estimated to affect 1 in 7,000 people. [6] Females are affected more often than males. [6] Most people with the condition develop symptoms before they are 40 years old. [6] It is a relatively common cause of sudden death along with Brugada syndrome and arrhythmogenic right ventricular dysplasia. [3]
Sudden unexplained nocturnal death syndrome may refer to: Brugada syndrome , a genetic disorder in which the electrical activity within the heart is abnormal Sudden arrhythmic death syndrome (SADS), a sudden unexpected death of adolescents and adults, mainly during sleep
Brugada syndrome can result in ventricular fibrillation and potentially death. It is a major cause of sudden unexpected cardiac death in young, otherwise healthy people. [ 11 ] While the characteristic patterns of Brugada syndrome on an electrocardiogram may be seen regularly, often the abnormal pattern is only seen spontaneously due to unknown ...
There is no cure for Brugada syndrome, but the condition may be treated using an implantable cardioverter defibrillator (ICD). [3] Medications to help control the abnormal heart rhythms include isoproterenol in those who are acutely unstable, and quinidine. [4] The family members of a patient with Brugada syndrome may require testing for the ...
In cardiology, genetic conditions such as Brugada syndrome can share features with related disorders caused by mutations in the same gene.An overlap syndrome can be seen whereby a mutation in the SCN5A gene encoding the cardiac sodium channel causes a reduction in the peak sodium current leading to the typical ECG features of Brugada syndrome, but which simultaneously increases the sustained ...
Blue baby syndrome can refer to conditions that cause cyanosis, or blueness of the skin, in babies as a result of low oxygen levels in the blood. This term has ...