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Globular bushy cells project large axons to the contralateral medial nucleus of the trapezoid body (MNTB), in the superior olivary complex where they synapse onto principal cells via a single calyx of Held, and several smaller collaterals synapse ipsilaterally in the posterior (PPO) and dorsolateral periolivary (DLPO) nuclei, lateral superior olive (LSO), and lateral nucleus of the trapezoid ...
The axons from the higher frequency organ of corti hair cells project to the dorsal portion of the ventral cochlear nucleus and the dorsal-medial portions of the dorsal cochlear nucleus. The mid frequency projections end up in between the two extremes; in this way the tonotopic organization that is established in the cochlea is preserved in the ...
The axons from the low-frequency region of the cochlea project to the ventral portion of the dorsal cochlear nucleus and the ventrolateral portions of the anteroventral cochlear nucleus. The axons from the high-frequency region project to the dorsal portion of the anteroventral cochlear nucleus and the uppermost dorsal portions of the dorsal ...
Math1/Math5 and FGF are two regulators essential for appropriate growth and development of the cochlear nucleus complex, which comprises both the ventral cochlear nucleus (VCN) and the dorsal cochlear nucleus (DCN). Sufficient FGF levels ensure proper morphology of the cochlear nuclei, while Math5 insures correct size and processing of the ...
The trapezoid body or ventral acoustic stria is a structure in the pontine tegmentum formed by the crossing-over (decussation) of a portion of the efferent second-order fibers of the ventral cochlear nucleus (anterior cochlear nucleus).
The lateral lemniscus is a tract of axons in the brainstem that carries information about sound from the cochlear nucleus to various brainstem nuclei and ultimately the contralateral inferior colliculus of the midbrain. Three distinct, primarily inhibitory, cellular groups are located interspersed within these fibers, and are thus named the ...
The spiral (cochlear) ganglion is a group of neuron cell bodies in the modiolus, the conical central axis of the cochlea. These bipolar neurons innervate the hair cells of the organ of Corti . They project their axons to the ventral and dorsal cochlear nuclei as the cochlear nerve , a branch of the vestibulocochlear nerve (CN VIII).
The majority of these axons are considered to be "round shaped" or type R. These R axons are mostly glutamatergic and contain round synaptic vesicles and form asymmetric synaptic junctions. [2] This is the largest of the nuclei and in humans it contains approximately 15,500 neurons. [1] Each MSO receives bilateral inputs from the right and left ...
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