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2. How Long Does It Take for L-Citrulline to Work for ED? - AOL

   www.aol.com/long-does-l-citrulline-ed-105700234.html

   One source recommends an L-citrulline dosage of 2,000 milligrams three times a day, or 1.76 grams of citrulline malate for every 1 gram of citrulline you might take for circulatory health.

3. Citrulline - Wikipedia

   en.wikipedia.org/wiki/Citrulline

   The organic compound citrulline is an α-amino acid. [2] Its name is derived from citrullus, the Latin word for watermelon.Although named and described by gastroenterologists since the late 19th century, it was first isolated from watermelon in 1914 by Japanese researchers Yatarō Koga (古賀彌太郎) and Ryō Ōtake (大嶽了) [3] [4] and further codified by Mitsunori Wada of Tokyo ...

4. Malic acid - Wikipedia

   en.wikipedia.org/wiki/Malic_acid

   Malate plays an important role in biochemistry. In the C4 carbon fixation process, malate is a source of CO 2 in the Calvin cycle. In the citric acid cycle, (S)-malate is an intermediate, formed by the addition of an -OH group on the si face of fumarate. It can also be formed from pyruvate via anaplerotic reactions.

5. Urea cycle - Wikipedia

   en.wikipedia.org/wiki/Urea_cycle

   3 L-citrulline 4 argininosuccinate 5 fumarate 6 L-arginine 7 urea ... This malate is then oxidized to oxaloacetate by cytosolic malate dehydrogenase, ...

6. Leucine - Wikipedia

   en.wikipedia.org/wiki/Leucine

   Leucine (symbol Leu or L) [3] is an essential amino acid that is used in the biosynthesis of proteins.Leucine is an α-amino acid, meaning it contains an α-amino group (which is in the protonated −NH 3 + form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO − form under biological conditions), and a side chain isobutyl group, making it a non ...

7. Ornithine transcarbamylase - Wikipedia

   en.wikipedia.org/wiki/Ornithine_transcarbamylase

   Ornithine transcarbamylase (OTC) (also called ornithine carbamoyltransferase) is an enzyme (EC 2.1.3.3) that catalyzes the reaction between carbamoyl phosphate (CP) and ornithine (Orn) to form citrulline (Cit) and phosphate (P i). There are two classes of OTC: anabolic and catabolic. This article focuses on anabolic OTC.