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Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin. [1] Constituting ~50–70% of cells in human islets, beta cells play a vital role in maintaining blood glucose levels. [2] Problems with beta cells can lead to disorders such ...
Pancreatic beta cell function (synonyms G β or, if calculated from fasting concentrations of insulin and glucose, HOMA-Beta or SPINA-GBeta) is one of the preconditions of euglycaemia, i.e. normal blood sugar regulation. It is defined as insulin secretory capacity, i.e. the maximum amount of insulin to be produced by beta cells in a given unit ...
It has also been demonstrated that alpha cells can spontaneously switch fate and transdifferentiate into beta cells in both healthy and diabetic human and mouse pancreatic islets, a possible future source for beta cell regeneration. [29] In fact, it has been found that islet morphology and endocrine differentiation are directly related. [30]
Beta cell; PP cell (F cell, gamma cell) Delta cell; Epsilon cell; Pharyngeal pouch. Thyroid gland Follicular cell; Parafollicular cell [3] Parathyroid gland.
Beta cell; This page is a redirect. The following categories are used to track and monitor this redirect: From the plural form: This is a redirect from a plural noun ...
A model of how ER stress is involved in β-cell death and type II diabetes mellitus. ER stress can be activated by a variety of factors. In experimental conditions, excessive lipid (which can happen following obesity, a common condition preceding type 2 diabetes) and pro-inflammatory cytokines (which can occur following an inflammation, a common cause for type 1 diabetes) can activate ER ...
B-cell may refer to : B cells, lymphocytes that mature in bone; Beta cells (β cells), in the pancreatic islets that produce insulin This page was last edited on 7 ...
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