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Instead of doping a surface directly, antimicrobial activity can be imparted to a surface by applying a coating containing antimicrobial agents such as biocides or silver nanoparticles. In the case of the latter, the nanoparticles can have beneficial effects on the structural properties of the coating along with their antibacterial effect. [27]
In doing so, Dow Corning had invented a durable, non-leaching, persistent, surface bonding antimicrobial effective against a wide range of unicellular microorganisms on a variety of surfaces. There are at least four private companies in the United States that are the primary manufacturers of Silane-Quats, which are widely known by various names ...
Antimicrobial copper-alloy touch surfaces can prevent frequently touched surfaces from serving as reservoirs for the spread of pathogenic microbes. This is especially true in healthcare facilities, where harmful viruses, bacteria, and fungi colonize and persist on doorknobs, push plates, handrails, tray tables, tap (faucet) handles, IV poles, HVAC systems, and other equipment. [1]
aPDT has shown antimicrobial efficacy against microbes on fruits, [121] [122] [123] vegetables, [121] [124] seafood, [125] [126] [127] and meat. [124] The efficacy of aPDT used in this way is dependent on several factors including wavelength of light, temperature, and food-related factors such as acidity, surface properties and water activity ...
Bacteria growth was reduced by 92% when polyethylenimine was tested as a coating surface for medical devices. [1] The activity of polyethylenimine is affected by the molecular weight of the polymer; low molecular weight polyethylenimine displays negligible activity, while displaying great antimicrobial activity in its high molecular weight form.
In general, the lower the surface tension of a liquid coating, the easier it will be to form a satisfactory wet film from it. The difference between the surface tension of a coating and the surface energy of a solid substrate to which a coating is applied affects how the liquid coating flows out over the substrate.
Antimicrobial use has been common practice for at least 2000 years. Ancient Egyptians and ancient Greeks used specific molds and plant extracts to treat infection. [5]In the 19th century, microbiologists such as Louis Pasteur and Jules Francois Joubert observed antagonism between some bacteria and discussed the merits of controlling these interactions in medicine. [6]
To overcome the increasing problem of antimicrobial resistance, it has become necessary to develop alternative and effective antimicrobial technologies to which pathogens will not be able to develop resistance. One possible approach is to cover a surface of medical devices with antimicrobial agents e.g. photosensitive organic molecules.