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FXR is expressed at high levels in the liver and intestine. Chenodeoxycholic acid and other bile acids are natural ligands for FXR. Similar to other nuclear receptors, when activated, FXR translocates to the cell nucleus, forms a dimer (in this case a heterodimer with RXR) and binds to hormone response elements on DNA, which up- or down-regulates the expression of certain genes.
Fragile X mental retardation syndrome-related protein 1 is a protein that in humans is encoded by the FXR1 gene. [5] [6] [7]The protein encoded by this gene is an RNA binding protein that interacts with the functionally similar proteins FMR1 and FXR2.
BIBS supply of breathing gas with higher oxygen content than the chamber atmosphere can solve this problem. If the atmosphere in a saturation habitat is contaminated, the inhabitants can use the available BIBS masks during the emergency and be supplied with non-contaminated breathing gas until the problem has been solved.
FXR may refer to: Farnesoid X receptor; Foxer, a World War II torpedo countermeasure; F. X. Reid, pseudonym of British computer science academic Mike W. Shields
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FireAid in Los Angeles inspired a community devastated by wildfires. We take you inside the benefit shows with Lady Gaga, Olivia Rodrigo and more.
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