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Temporal lobe epilepsy is the most common focal onset epilepsy, and 80% of temporal lobe epilepsy is mesial (medial) temporal lobe epilepsy, temporal lobe epilepsy arising from the inner part of the temporal lobe that may involve the hippocampus, parahippocampal gyrus or amygdala. [2] [11] The less common lateral temporal lobe or neocortical ...
Alternatively, autobiographical memory loss may result from subtle changes in the temporal lobe which gives rise to temporal lobe epilepsy and to memory problems. The mechanism and etiology of this phenomenon remain controversial, especially as it is impossible to rule out prior subclinical epileptic activity which could be responsible for a ...
An overlap between symptoms can occur as the disease progresses and spreads through the brain regions. [14] Structural MRI scans often reveal frontal lobe and/or anterior temporal lobe atrophy, but in early cases the scan may seem normal. Atrophy can be either bilateral or asymmetric. [13]
The hallmark symptom of LATE is a progressive memory loss that predominantly affects short-term and episodic memory. [1] This impairment is often severe enough to interfere with daily functioning and usually remains the chief neurologic deficit, unlike other types of dementia in which non-memory cognitive domains and behavioral changes might be noted earlier or more prominently. [1]
SD is a clinically defined syndrome but is associated with predominantly temporal lobe atrophy (left greater than right) and hence is sometimes called temporal variant FTLD (tvFTLD). [7] SD is one of the three variants of primary progressive aphasia (PPA), which results from neurodegenerative disorders such as FTLD or Alzheimer's disease .
The most common comorbid disorders are depression and anxiety, [16] although cases of depersonalization disorder without symptoms of either do exist. Comorbid obsessive/compulsive behaviors may exist as attempts to deal with depersonalization, such as checking whether symptoms have changed and avoiding behavioral and cognitive factors that ...
Klüver–Bucy syndrome has been shown to occur more in adults than in children. [13] In children, certain conditions such as herpes simplex encephalitis have the potential to manifest the syndrome. [13] Children exhibit many of the same symptoms as adults with Klüver–Bucy syndrome, but they display these symptoms in different ways than ...
This disorder is often associated with brain lesions in the dominant (usually left) hemisphere including the angular and supramarginal gyri (Brodmann area 39 and 40 respectively) near the temporal and parietal lobe junction. There is significant debate in the scientific literature as to whether Gerstmann syndrome truly represents a unified ...