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Caustic ingestion occurs when someone accidentally or deliberately ingests a caustic or corrosive substance. Depending on the nature of the substance, the duration of exposure and other factors it can lead to varying degrees of damage to the oral mucosa , the esophagus , and the lining of the stomach .
By individual year of age, 1- and 2-year-old children have the highest incidence of these injuries, with rates approximately 50% higher than the highest-risk adult group (25 years), and 13 times higher than the rate among 7-year-olds. [4] Further research identified laundry detergent pods as a major source of injury among small children. [5]
Methanol toxicity (also methanol poisoning) is poisoning from methanol, characteristically via ingestion. [1] Symptoms may include an altered/decreased level of consciousness, poor or no coordination, vomiting, abdominal pain, and a specific smell on the breath. [1] [2] Decreased vision may start as early as twelve hours after exposure. [2]
When ingested, chloroform causes symptoms similar to those seen after inhalation. Serious illness has followed ingestion of 7.5 g (0.26 oz). The mean lethal oral dose in an adult is estimated at 45 g (1.6 oz). [37] The anesthetic use of chloroform has been discontinued, because it caused deaths from respiratory failure and cardiac arrhythmias.
Treatment for antifreeze poisoning needs to be started as soon after ingestion as possible to be effective; the earlier treatment is started, the greater the chance of survival. [ 6 ] [ 43 ] Cats must be treated within 3 hours of ingesting of antifreeze to be effective, while dogs must be treated within 8–12 hours of ingestion. [ 9 ]
Chemical burns may occur through direct contact on body surfaces, including skin and eyes, via inhalation, and/or by ingestion. Substances that diffuse efficiently in human tissue, e.g., hydrofluoric acid , sulfur mustard , and dimethyl sulfate , may not react immediately, but instead produce the burns and inflammation hours after the contact.
Symptoms of HF exposure include irritation of the eyes, skin, nose, and throat; eye and skin burns; and bone damage. [3] Complications may occur due to fluoride toxicity. [1] Once absorbed into blood through the skin, [1] it reacts with blood calcium and may cause cardiac arrest.
Infant botulism results from the ingestion of the C. botulinum spores, and subsequent colonization of the small intestine. The infant gut may be colonized when the composition of the intestinal microflora (normal flora) is insufficient to competitively inhibit the growth of C. botulinum and levels of bile acids (which normally inhibit ...