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The paramesonephric ducts play a critical role in the female reproductive tract and differentiate to form the uterine tubes, uterus, superior vagina as well as the uterine cervix. Many types of disorders can occur when this system is disrupted ranging from uterine and vaginal agenesis to the duplication of unwanted cells of the uterus and vagina.
In the female, the paramesonephric ducts persist and undergo further development. The portions which lie in the genital cord [citation needed] fuse to form the uterus and vagina. This fusion of the paramesonephric ducts begins in the third month, and the septum formed by their fused medial walls disappears from below upward.
The internal genitalia consist of two accessory ducts: mesonephric ducts (male) and paramesonephric ducts (female). The mesonephric system is the precursor to the male genitalia and the paramesonephric to the female reproductive system. [8] As development proceeds, one of the pairs of ducts develops while the other regresses.
Female Male Gonad: Ovary: Testicle: Rete ovarii: Rete testis: Paramesonephric ducts (Müllerian ducts) Fallopian tube: Appendix testis: Uterus, cervix, vagina [1] Prostatic utricle: Mesonephric ducts (Wolffian ducts) Epoophoron: Epididymis: Gartner's duct: Vas deferens: Seminal vesicle: Mesonephric tubules: Paroophoron: Paradidymis: Urogenital ...
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The term vagina is from Latin vāgīna, meaning "sheath" or "scabbard". [1] The vagina may also be referred to as the birth canal in the context of pregnancy and childbirth. [2] [3] Although by its dictionary and anatomical definitions, the term vagina refers exclusively to the specific internal structure, it is colloquially used to refer to the vulva or to both the vagina and vulva.
Embryos are formed with Wolffian and Mullerian ducts, which will either become the male or female reproductive tract, respectively. [8] In a male embryo, the testicular cords will induce the development of the Wolffian duct into the vas deferens, epididymis and the seminal vesicle and cause the repression and regression of the Mullerian duct. [4]
It has been suggested that embryos with a higher expression of Dmrt1 expression develop into males while embryos with a lower expression are led to female development. [ 1 ] In the mouse gonadal primordium, the genital ridge, which forms from intermediate mesoderm, becomes morphologically distinct at E10.5.