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Lutetium (177 Lu) oxodotreotide or 177 Lu dotatate, brand name Lutathera, is a chelated complex of a radioisotope of the element lutetium with dotatate, used in peptide receptor radionuclide therapy. Specifically, it is used in the treatment of cancers which express somatostatin receptors. [5] It is a radiolabeled somatostatin analog. [3] [6] [7]
Radiation from lutetium (177 Lu) oxodotreotide can cause damage when the medicine passes through tubules in the kidney. [45] Arginine/lysine can be used to reduce renal radiation exposure during peptide receptor radionuclide therapy with lutetium (177 Lu) oxodotreotide. [45]
DOTA-TATE can be reacted with the radionuclides gallium-68 (T 1/2 = 68 min), lutetium-177 (T 1/2 = 6.65 d) and copper-64 (T 1/2 = 12.7 h) to form radiopharmaceuticals for positron emission tomography (PET) imaging or radionuclide therapy. 177 Lu DOTA-TATE therapy is a form of peptide receptor radionuclide therapy (PRRT) which targets ...
Naturally occurring lutetium (71 Lu) is composed of one stable isotope 175 Lu (97.41% natural abundance) and one long-lived radioisotope, 176 Lu with a half-life of 37 billion years (2.59% natural abundance).
A new opioid-free pain medication was approved by the U.S. Food and Drug Administration (FDA) on Thursday, marking a non-addictive alternative for patients.. Journavx (suzetrigine), made by Vertex ...
Mayo Clinic, Rochester, was ranked in the top 10 in all but one of 16 specialties, in the top 4 in 13 specialties, and was the #1 ranked hospital in 8 of the 12 data-driven specialties. This year U.S. News expanded their common procedures and conditions list to 9 individual measures, and Mayo was one of fewer than 70 hospitals to score High ...
Concerns about exposure to Red Dye No. 3 in children and its potential association with adolescent hyperactivity have also been raised over the years — however, in a 2011 review, the FDA found ...
“Eating a well-balanced breakfast with the right amount of protein, carbs and fat jump-starts your metabolism, provides essential energy for the day, and sets the tone for healthier food choices ...