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Head CT showing periventricular white matter lesions. Leukoaraiosis is a particular abnormal change in appearance of white matter near the lateral ventricles. It is often seen in aged individuals, but sometimes in young adults. [1] [2] On MRI, leukoaraiosis changes appear as white matter hyperintensities (WMHs) in T2 FLAIR images.
For example, deep white matter hyperintensities are 2.5 to 3 times more likely to occur in bipolar disorder and major depressive disorder than control subjects. [3] [4] WMH volume, calculated as a potential diagnostic measure, has been shown to correlate to certain cognitive factors. [5]
The Cauchy distribution, an example of a distribution which does not have an expected value or a variance. In physics it is usually called a Lorentzian profile, and is associated with many processes, including resonance energy distribution, impact and natural spectral line broadening and quadratic stark line broadening.
The simplest case of a normal distribution is known as the standard normal distribution or unit normal distribution. This is a special case when μ = 0 {\textstyle \mu =0} and σ 2 = 1 {\textstyle \sigma ^{2}=1} , and it is described by this probability density function (or density): φ ( z ) = e − z 2 2 2 π . {\displaystyle \varphi (z ...
White matter refers to areas of the central nervous system that are mainly made up of myelinated axons, also called tracts. [1] Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution of action potentials, acting as a relay and coordinating communication between different brain regions. [2]
The equidensity contours of a non-singular multivariate normal distribution are ellipsoids (i.e. affine transformations of hyperspheres) centered at the mean. [29] Hence the multivariate normal distribution is an example of the class of elliptical distributions.
The product of independent random variables X and Y may belong to the same family of distribution as X and Y: Bernoulli distribution and log-normal distribution. Example: If X 1 and X 2 are independent log-normal random variables with parameters (μ 1, σ 2 1) and (μ 2, σ 2 2) respectively, then X 1 X 2 is a log-normal random variable with ...
The gray matter remains normal in all characteristics while the white matter changes texture, becoming soft and gelatinous. Rarefaction of the white matter is seen through light microscopy and the small number of axons and U-fibers that were affected can also be seen. Numerous small cavities in the white matter are also apparent.