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The fluorescent treponemal antibody absorption (FTA-ABS) test is a diagnostic test for syphilis.Using antibodies specific for the Treponema pallidum species, such tests would be assumed to be more specific than non-treponemal testing such as VDRL but have been shown repeatedly to be sensitive but not specific for the diagnosis of neurosyphilis in cerebrospinal fluid (CSF).
In the test, red blood cells (erythrocytes) are sensitized with antigens from T. pallidum pallidum. The cells then aggregate on the surface of a test dish if exposed to the serum of a patient with syphilis. It is used as a confirmatory test for syphilis infection. A negative test result shows a tight button or spot of red blood cells on the ...
This test is not done on spinal fluid. The MHA-TP test is rarely used any more. [4] Treponema pallidum particle agglutination assay and the Toluidine red unheated serum test (TRUST), which may be used to confirm a positive VDRL result, are more specific for syphilis than non-treponemal tests and in the presence of a positive test, more
Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. Syphilis is typically spread through direct contact with a syphilis sore , known as a chancre, during ...
The new test received FDA authorization after the company submitted data from clinical trials showing that the First To Know Syphilis Test identified a positive specimen 93.4% of the time.
Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
US FDA approves first at-home syphilis test. August 16, 2024 at 11:12 AM (Reuters) -The U.S. Food and Drug Administration on Friday granted marketing authorization to the first at-home, over-the ...
The rapid plasma reagin test (RPR test or RPR titer) is a type of rapid diagnostic test that looks for non-specific antibodies in the blood of the patient that may indicate an infection by syphilis or related non-venereal treponematoses. It is one of several nontreponemal tests for syphilis (along with the Wassermann test and the VDRL test).
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