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Golgi's method is a silver staining technique that is used to visualize nervous tissue under light microscopy. The method was discovered by Camillo Golgi , an Italian physician and scientist , who published the first picture made with the technique in 1873. [ 1 ]
Confocal microscope image of cerebellar Purkinje cells expressing tdTomato. These cells are some of the largest neurons in the human brain (Betz cells being the largest), [5] with an intricately elaborate dendritic arbor, characterized by a large number of dendritic spines. Purkinje cells are found within the Purkinje layer in the cerebellum.
Nissl bodies show changes under various physiological conditions and in pathological conditions such as axonotmesis, during which they may dissolve and largely disappear (chromatolysis). If the neuron is successful in repairing the damage, the Nissl bodies gradually reappear and return to their characteristic distribution within the cell.
Nervous tissue, also called neural tissue, is the main tissue component of the nervous system.The nervous system regulates and controls body functions and activity. It consists of two parts: the central nervous system (CNS) comprising the brain and spinal cord, and the peripheral nervous system (PNS) comprising the branching peripheral nerves.
In cellular neuroscience, the soma (pl.: somata or somas; from Greek σῶμα (sôma) 'body'), neurocyton, or cell body is the bulbous, non-process portion of a neuron or other brain cell type, containing the cell nucleus.
One small study found that men have more white matter than women both in volume and in length of myelinated axons, and that volume and length reduced with age. (This study only included 36 participants. [6]) At the age of 20, the total length of myelinated fibers in men is 176,000 km while that of a woman is 149,000 km.
Oligodendrocytes are a type of glial cell, non-neuronal cells in the central nervous system.They arise during development from oligodendrocyte precursor cells (OPCs), [8] which can be identified by their expression of a number of antigens, including the ganglioside GD3, [9] [10] [11] the NG2 chondroitin sulfate proteoglycan, and the platelet-derived growth factor-alpha receptor subunit (PDGF ...
Recent studies using cross-sectional neuroimaging have shown that by around the age of 8 the volume of grey matter begins to decrease. [4] However, the density of grey matter appears to increase as a child develops into early adulthood. [4] Males tend to exhibit grey matter of increased volume but lower density than that of females. [5]