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While use during pregnancy is not recommended, risk appears to be low. [6] The use of other medications in this class appear to be safe while breastfeeding; however, the safety of levofloxacin is unclear. [6] Levofloxacin was patented in 1985 and approved for medical use in the United States in 1996.
Breastfeeding and medications is the description of the medications that can be used by a breastfeeding mother, and the balance between maternal health and the safety of the breastfeeding infant. [1] [2] Medications, when administered to breastfeeding mothers, almost always are transferred to breast milk, albeit usually in small quantities. [3]
Moxifloxacin is an antibiotic, used to treat bacterial infections, [4] including pneumonia, conjunctivitis, endocarditis, tuberculosis, and sinusitis. [4] [5] It can be given by mouth, by injection into a vein, and as an eye drop.
Contraindications to breastfeeding are those conditions that could compromise the health of the infant if breast milk from their mother is consumed. Examples include galactosemia , untreated HIV , untreated active tuberculosis , Human T-lymphotropic virus 1 or II , uses illicit drugs , or mothers undergoing chemotherapy or radiation treatment .
While metamizole is a relatively safe medication, [24] it is not entirely devoid of adverse effects. [ 24 ] Metamizole has a potential of blood-related toxicity (blood dyscrasias ), but causes less kidney , cardiovascular , and gastrointestinal toxicity than non-steroidal anti-inflammatory drugs (NSAIDs). [ 11 ]
While the company that makes it does not recommend use during breastfeeding, use is believed to be safe if the baby is otherwise healthy. [2] It is in the sulfonamide class of medications. [1] Sulfadiazine was approved for medical use in the United States in 1941. [1] [5] It is on the World Health Organization's List of Essential Medicines. [6]
While most medications on the list are available as generic products, being under patent does not preclude inclusion. [7] The first list was published in 1977 and included 208 medications. [8] [2] [9] The WHO updates the list every two years. [10]
The fosfomycin molecule has an epoxide or oxirane ring, which is highly strained and thus very reactive. [citation needed]Fosfomycin has broad antibacterial activity against both Gram-positive and Gram-negative pathogens, with useful activity against E. faecalis, E. coli, and various Gram-negatives such as Citrobacter and Proteus.
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