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In this population, a biopsy of the gastrocnemius muscle is a useful tool in correctly diagnosing the person. The presence of a noncaseating epithelioid granuloma in a gastrocnemius specimen is definitive evidence of sarcoidosis, as other tuberculoid and fungal diseases extremely rarely present histologically in this muscle. [105]
Granuloma; Picture of a granuloma (without necrosis) as seen through a microscope on a glass slide: The tissue on the slide is stained with two standard dyes (hematoxylin: blue, eosin: pink) to make it visible. The granuloma in this picture was found in a lymph node of a patient with a Mycobacterium avium infection. Specialty: Pathology
The acute form can be characterized by poorly formed noncaseating interstitial granulomas and mononuclear cell infiltration in a peribronchial distribution with prominent giant cells. [1] The subacute, or intermittent, form produces more well-formed noncaseating granulomas, bronchiolitis with or without organizing pneumonia , and interstitial ...
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The more precise terminology is "non-necrotizing" or "necrotizing rather than "non-caseous or "caseous," as Yale Rosen, M.D. explained: "The use of the terms "caseating" and "non-caseating" to describe the microscopic appearance of granulomas, although prevalent, is inappropriate since the term "caseous" applies only to the grossly visible ...
Caseous necrosis in the kidney. In caseous necrosis no histological architecture is preserved (unlike with coagulative necrosis). [5] [6] On microscopic examination with H&E staining, the area is acellular, characterised by amorphous, roughly granular eosinophilic debris of now dead cells, [6] also containing interspearsed haematoxyphilic remnants of cell nucleus contents. [5]
Epithelioid cells gather around the focus of necrosis, in direct contact with the necrotic masses, forming a kind of boundary zone.. Structurally, epithelioid cells (when examined by light microscopy after stained with hematoxylin and eosin), are elongated, with finely granular, pale eosinophilic (pink) cytoplasm, and central, ovoid nuclei (oval or elongate), which are less dense than that of ...
Signs of ear infection include shaking of the head, and scratching at or under the ear. Some animals may also paw the ear or try to rub it on other objects to relieve pain and discomfort. Ear infections often result in a darker red ear, dirt in the ear, or a general inflamed appearance. Chronic allergic otitis externa in a dog with atopic ...