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An ejection fraction (EF) is the volumetric fraction (or portion of the total) of fluid (usually blood) ejected from a chamber (usually the heart) with each contraction (or heartbeat). It can refer to the cardiac atrium , [ 1 ] ventricle , [ 2 ] gall bladder, [ 3 ] or leg veins, [ 4 ] although if unspecified it usually refers to the left ...
This is defined as a left ventricular ejection fraction (LVEF) of 40% or less. About half of heart failure patients have a reduced ejection fraction. [2] Other types of heart failure are heart failure with mildly reduced ejection fraction (LVEF between 40% and 50%) and heart failure with preserved ejection fraction (LVEF 50% or higher). [1] [3]
Left-sided heart failure may be present with a reduced ejection fraction or with a preserved ejection fraction. [10] Heart failure is not the same as cardiac arrest, in which blood flow stops completely due to the failure of the heart to pump. [12] [13] Diagnosis is based on symptoms, physical findings, and echocardiography. [6]
Normal range is 25–45%, Mild is 20–25%, Moderate is 15–20%, and Severe is <15%. [26] Cardiology Diagnostic Tests Midwall fractional shortening may also be used to measure diastolic/systolic changes for inter-ventricular septal dimensions [ 27 ] and posterior wall dimensions.
Major factors influencing cardiac output – heart rate and stroke volume, both of which are variable. [1]In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , Ë™, or Ë™, [2] is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured ...
Heart failure with reduced ejection fraction (HFrEF) >$10 billion addressable market potential. Chronic low back pain (CLBP) >$10 billion addressable market potential. Additional potential multi-billion-dollar opportunities from existing and future product pipeline based on existing technology platforms.
This is particularly if there are any ongoing signs of heart failure, with a low left ventricular ejection fraction and a New York Heart Association grade II or III after 40 days of the infarction. [72] Defibrillators detect potentially fatal arrhythmia and deliver an electrical shock to the person to depolarize a critical mass of the heart muscle.
There is some evidence for the benefits of coenzyme Q10 in treating heart failure. [33] [34] [35] K-strophanthin may improve functional performance in patients with severe cardiac decompensation while digoxin raises cardiac output and ejection fraction only at rest. [36]
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