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Triclocarban has been used as an antimicrobial and antifungal compound since the 1960s. [5] It was commonly found in personal care products as an antimicrobial in soaps, lotions, deodorants, toothpaste, and plastic. [6] As of 2005 about 80% of all antimicrobial bar soap sold in the United States contained triclocarban. [5]
The advisory panel first met on June 29, 1972, and the agency published its proposed rule on Sept 13, 1974. The initial rule applied to, "OTC products containing antimicrobial ingredients for topical human use, which includes soaps, surgical scrubs, skin washes, skin cleansers, first aid preparations and additional products defined by the panel."
Nystatin, sold under the brand name Mycostatin among others, is an antifungal medication. [1] It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. [1] It may also be used to prevent candidiasis in those who are at high risk. [1]
Miconazole is a widely used topical antifungal medication for the treatment of many fungal infections, namely skin infections, nail infections and vaginal candidiasis. The drug is usually formulated in creams, powders and sprays. However, it is suggested that patients developing acute porphyrias should avoid using this drug.
Ketoconazole, sold under the brand name Nizoral, among others, is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. [11] Applied to the skin it is used for fungal skin infections such as tinea, cutaneous candidiasis, pityriasis versicolor, dandruff, and seborrheic dermatitis. [12]
Potassium permanganate is used as a medication for a number of skin conditions. [2] This includes fungal infections of the foot, impetigo, pemphigus, superficial wounds, dermatitis, and tropical ulcers. [3] [2] For tropical ulcers it is used together with procaine benzylpenicillin. [2] [3] It can be applied as a soaked dressing or a bath. [2]
Tolnaftate [1] sold under the brand name TAGRID among, others is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription in most jurisdictions. It is supplied as a cream, powder, spray, liquid, and liquid aerosol . [ 2 ]
Sudocrem (/ ˈ s u d ə k r ɛ m / or / ˈ s u d ə k r i m / in Ireland) [3] is an over-the-counter medicated cream aimed primarily at the treatment of irritant diaper dermatitis.It contains a water-repellent base (consisting of oils/waxes); protective and moisturizer agents; antibiotic and antifungal agents; and a weak anesthetic.
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