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A study conducted by the Aquaculture Institute looked into the effects of cannabis oil on the metabolism and immune system of the Nile tilapia (Oreochromis niloticus). They found that cannabis has no measurable effect on the white blood cell count or plasma protein concentration, and therefore has no effect on the immune system of the Nile tilapia.
A cannabis edible, also known as a cannabis-infused food or simply an edible, is a food item (either homemade or produced commercially) that contains decarboxylated cannabinoids (cannabinoid acids converted to their orally bioactive form) from cannabis extract as an active ingredient. [1]
It was found that the major metabolites of CBD in humans (7-OH-CBD and 7-COOH-CBD) are not prevalent in dogs, while 6-OH-CBD was found to be the primary metabolite in dogs receiving a CBD-enriched cannabis-derived herbal extract, [185] suggesting that canine and human CBD metabolic route might be somewhat different.
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Scientists aren’t sure if cannabis use leads to anxiety, or if anxiety symptoms in many cannabis users are pre-existing but underdiagnosed, prompting users’ attempt to self-medicate.
In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index, [21] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation. [22]
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