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Top: An ancestral gene duplication produces two paralogs (histone H1.1 and 1.2). A speciation event produces orthologs in the two daughter species (human and chimpanzee). Bottom: in a separate species , a gene has a similar function (histone-like nucleoid-structuring protein) but has a separate evolutionary origin and so is an analog.
The term "ortholog" was coined in 1970 by the molecular evolutionist Walter Fitch. [41] Homologous sequences are paralogous if they were created by a duplication event within the genome. For gene duplication events, if a gene in an organism is duplicated, the two copies are paralogous. They can shape the structure of whole genomes and thus ...
English: Top: An ancestral gene duplicates to produce two paralogs (Genes A and B). A speciation event produces orthologs in the two daughter species. Bottom: in a separate species, an unrelated gene has a similar function (Gene C) but has a separate evolutionary origin and so is an analog.
The cell division cycle protein 20 homolog is an essential regulator of cell division that is encoded by the CDC20 gene [5] [6] in humans. To the best of current knowledge its most important function is to activate the anaphase promoting complex (APC/C), a large 11-13 subunit complex that initiates chromatid separation and entrance into anaphase .
A speciation event produces orthologs in the two daughter species (human and chimpanzee). Bottom: in a separate species ( E. coli ), an gene has a similar function ( histone-like nucleoid-structuring protein ) but has a separate evolutionary origin and so is an analog .
The secondary cell wall, a thick layer formed inside the primary cell wall after the cell is fully grown. It is not found in all cell types. It is not found in all cell types. Some cells, such as the conducting cells in xylem , possess a secondary wall containing lignin , which strengthens and waterproofs the wall.
Synteny (in the modern sense) between human and mouse chromosomes. Colors in the human chromosomes indicate regions homologous with parts of the mouse chromosome of the same color. For instance, sequences homologous to mouse chromosome 1 are primarily on human chromosomes 1 and 2, but also 6, 8, and 18.
Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. [ 5 ] [ 6 ] SMAD3 is a member of the SMAD family of proteins.