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Little is known about the long-term side effects of hormone or puberty blockers in children with gender dysphoria. Although puberty blockers are known to be safe and physically reversible treatment if stopped in the short term, it is also not known whether hormone blockers affect the development of factors like bone mineral density, brain ...
Antiandrogens are also used as a component of feminizing hormone therapy for transgender women and as puberty blockers in transgender girls. [4] Side effects of antiandrogens depend on the type of antiandrogen and the specific antiandrogen in question.
"The best available evidence reporting on the effects of [hormone therapy] in individuals experiencing [gender dysphoria] ranged from moderate to high certainty for cardiovascular events, and low ...
As with all hormonal therapies, GnRH antagonists are commonly associated with hormonal side effects such as hot flushes, headache, nausea and weight gain. [18] [19] [20] When used in fertility treatment they can also be associated with abdominal pain and ovarian hyperstimulation.
Some of the effects of hormone therapy are irreversible, but coming off HRT can cause withdrawal symptoms and changes to a person’s weight and skin. It is a lifelong treatment.
These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30] In the EPC trial, at a median follow-up of 7.4 years, breast pain and gynecomastia respectively occurred in 73.6% and 68.8% of men treated with 150 mg/day bicalutamide ...
Breen’s suit claims Olson-Kennedy’s clinic put her on puberty blockers when she was just 12, started her on hormone therapy at 13 and performed a double mastectomy on her at 14.
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
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