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Drosophila embryogenesis, the process by which Drosophila (fruit fly) embryos form, is a favorite model system for genetics and developmental biology. The study of its embryogenesis unlocked the century-long puzzle of how development was controlled, creating the field of evolutionary developmental biology . [ 1 ]
For example, the gene called Bicoid regulates the formation of the embryo's anterior end, and its absence leads to an embryo lacking a head. Zygotic genes: These genes are activated in later stages of embryo development when the fruit fly embryo begins to produce its own genetic products. For example, the hunchback gene regulates the formation ...
Gal4 is a modular protein consisting broadly of a DNA-binding domain and an activation domain. The UAS to which GAL4 binds is CGG-N 11-CCG, where N can be any base. [6] Although GAL4 is a yeast protein not normally present in other organisms it has been shown to work as a transcription activator in a variety of organisms such as Drosophila, [7] and human cells, highlighting that the same ...
FlyBase is an online bioinformatics database and the primary repository of genetic and molecular data for the insect family Drosophilidae. [1] For the most extensively studied species and model organism, Drosophila melanogaster, a wide range of data are presented in different formats.
The gap genes code for transcription factors that regulate the expression of pair-rule genes and homeotic genes [8] by competing for binding to their enhancer regions. It has been demonstrated that gap gene expression in the Drosophila blastoderm exhibit a property called canalization, a property of developing organisms to produce a consistent phenotype despite variations in genotype or ...
The Drosophilidae are a diverse, cosmopolitan family of flies, which includes species called fruit flies, although they are more accurately referred to as vinegar or pomace flies. [1] Another distantly related family of flies, Tephritidae , are true fruit flies because they are frugivorous, and include apple maggot flies and many pests.
Figure 6b: A common fruit fly (Drosophila melanogaster) William R. Rice and George W. Salt found experimental evidence of sympatric speciation in the common fruit fly. They collected a population of Drosophila melanogaster from Davis, California, and placed the pupae into a habitat maze. Newborn flies had to investigate the maze to find food.
Balancer chromosomes were first used in the fruit fly by Hermann Muller, who pioneered the use of radiation for organismal mutagenesis. [2]In the modern usage of balancer chromosomes, random mutations are first induced by exposing living organisms with otherwise normal chromosomes to substances which cause DNA damage; in flies and nematodes, this usually occurs by feeding larvae ethyl ...