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GAPDH Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1U8F, 1ZNQ, 3GPD, 4WNC, 4WNI Identifiers Aliases GAPDH, GAPD, G3PD, HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase External IDs OMIM: 138400 ; MGI: 5434255 ; HomoloGene: 107053 ; GeneCards: GAPDH ; OMA: GAPDH - orthologs Gene location (Human) Chr. Chromosome 12 (human) Band 12p13.31 Start 6,534,512 bp End ...
Housekeeping genes account for majority of the active genes in the genome, and their expression is obviously vital to survival. The housekeeping gene expression levels are fine-tuned to meet the metabolic requirements in various tissues.
This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism.Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate.
Patients with a Gene A signature have better percent survival than patients with a Gene B signature. In a 2001 study published in the Proceedings of the National Academy of Sciences, Sørlie et al. [10] further stratified the classifications described by Perou et al. [9] and explored the clinical value of these breast cancer subtypes. The ...
The difference in disease-free survival rates (but not the overall survival rates) between individuals with PABC and ALIC was significant. [31] Further studies with larger numbers of patients are required to further define the features of ALIC and accurately compare its long-term prognosis to PACB as well as other breast cancer tumors. [1]
HRT Atlas allows searching of a complete list of reliable candidate reference genes and transcripts for RT-qPCR normalization in more than 120 human and mouse tissues or cell types. The database also offers some empirically validated primers and predicted modifiers (disease and small molecules) of the expression of these reference genes.
Females are at an increased risk of developing breast cancer, which is the most common malignancy observed in Cowden's patients. [3] Although some cases have been reported, there is not enough evidence to indicate an association between Cowden syndrome and the development of male breast cancer. [ 3 ]
This is a list of major breast cancer cell lines that are primarily used in breast cancer research. [Notes 1] List of cell lines. Cell line Primary tumor