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  2. Coronavirus spike protein - Wikipedia

    en.wikipedia.org/wiki/Coronavirus_spike_protein

    The function of the spike glycoprotein is to mediate viral entry into the host cell by first interacting with molecules on the exterior cell surface and then fusing the viral and cellular membranes. Spike glycoprotein is a class I fusion protein that contains two regions, known as S1 and S2, responsible for these two functions.

  3. Coronavirus membrane protein - Wikipedia

    en.wikipedia.org/wiki/Coronavirus_membrane_protein

    M is a glycoprotein whose glycosylation varies according to coronavirus subgroup; N-linked glycosylation is typically found in the alpha and gamma groups while O-linked glycosylation is typically found in the beta group. [8] [9] There are some exceptions; for example, in SARS-CoV, a betacoronavirus, the M protein has one N-glycosylation site.

  4. Spike protein - Wikipedia

    en.wikipedia.org/wiki/Spike_protein

    Coronaviruses exhibit coronavirus spike protein, also known as the S protein, on their surfaces; S is a class I fusion protein and is responsible for mediating viral entry as the first step in viral infection. [10] It is highly antigenic and accounts for most antibodies produced by the immune system in response to infection.

  5. Coronavirus can transform pancreas cell function; certain ...

    www.aol.com/coronavirus-transform-pancreas-cell...

    When the coronavirus infects cells, it not only impairs their activity but can also change their function, new findings suggest. For example, when insulin-producing beta cells in the pancreas ...

  6. Coronavirus - Wikipedia

    en.wikipedia.org/wiki/Coronavirus

    The earliest reports of a coronavirus infection in animals occurred in the late 1920s, when an acute respiratory infection of domesticated chickens emerged in North America. [15] Arthur Schalk and M.C. Hawn in 1931 made the first detailed report which described a new respiratory infection of chickens in North Dakota.

  7. Coronaviridae - Wikipedia

    en.wikipedia.org/wiki/Coronaviridae

    Replication cycle of a coronavirus. The 5' and 3' ends of the genome have a cap and poly(A) tract, respectively.The viral envelope, obtained by budding through membranes of the endoplasmic reticulum (ER) or Golgi apparatus, invariably contains two virus-specified glycoprotein species, known as the spike (S) and membrane (M) proteins.

  8. Hemagglutinin esterase - Wikipedia

    en.wikipedia.org/wiki/Hemagglutinin_esterase

    Certain studies revealed that coronavirus and toroviruses HE was originated from HEF glycoprotein that is found in influenza C viruses which resulted from alteration of hemagglutinin esterase from a trimer into a dimer glycoprotein. [1] During this process, the receptor destroying enzyme acetyl esterase domain stayed unchanged.

  9. 3C-like protease - Wikipedia

    en.wikipedia.org/wiki/3C-like_protease

    The Enzyme Commission refers to this family as SARS coronavirus main proteinase (M pro; EC 3.4.22.69). The 3CL protease corresponds to coronavirus nonstructural protein 5 (nsp5). The "3C" in the common name refers to the 3C protease (3C pro ) which is a homologous protease found in picornaviruses .