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Common side effects include bleeding and nausea. [8] [9] Other side effects may include bleeding around the spine and allergic reactions. [8] Use is not recommended during pregnancy or breastfeeding. [1] [9] Use appears to be relatively safe in those with mild kidney problems. [9] Compared to warfarin it has fewer interactions with other ...
Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain . [ 2 ]
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:
Cialis has several common side effects, many of which also happen with other drugs used to treat ED, like sildenafil (generic Viagra®), vardenafil , and avanafil (Stendra®).
These two hydrogen bonds serve an important role directing the drug into the S1 and S4 subsites of FXa. The first hydrogen bond is a strong interaction which comes from the carbonyl oxygen of the oxazolidinone core of rivaroxaban. The second hydrogen bond is a weaker interaction and comes from the amino group of the clorothiophene carboxamide ...
The action of drugs on the human body (or any other organism's body) is called pharmacodynamics, and the body's response to drugs is called pharmacokinetics. The drugs that enter an individual tend to stimulate certain receptors, ion channels, act on enzymes or transport proteins. As a result, they cause the human body to react in a specific way.
Common side effects include bleeding. [8] Other serious side effects may include spinal hematoma and anaphylaxis. [8] It is unclear if use in pregnancy and breastfeeding is safe. [1] Compared to warfarin it has fewer interactions with other medications. [9] It works by blocking the activity of the clotting protein factor Xa. [8]
Common side effects include diarrhea, headache, and high blood pressure. [10] Serious side effects may include infections, cancer , and pulmonary embolism . [ 10 ] [ 11 ] In 2019, the safety committee of the European Medicines Agency began a review of tofacitinib and recommended that doctors temporarily not prescribe the 10 mg twice-daily dose ...