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Glulisine is rapid acting insulin analog from Sanofi-Aventis, approved for use with a regular syringe, in an insulin pump. Standard syringe delivery is also an option. It is sold under the name Apidra. The FDA-approved label states that it differs from regular human insulin by its rapid onset and shorter duration of action. [3]
Allergists explain what ingredients to look for in OTC allergy medications, and recommend their top picks for non-drowsy, pollen, runny nose, and pet dander.
Insulin lispro, sold under the brand name Humalog among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [5] It is delivered subcutaneously either by injection or from an insulin pump .
A short-acting insulin is used to simulate the endogenous insulin surge produced in anticipation of eating. Regular insulin, lispro, aspart and glulisine can be used for this purpose. Regular insulin should be given with about a 30-minute lead-time prior to the meal to be maximally effective and to minimize the possibility of hypoglycemia.
Insulin lispro (Humalog) Insulin aspart (Novolog) Insulin glulisine (Apidra) Examples of short-acting insulins (peak 2–4 hours) are: Regular insulin (Humulin R, Novolin R) Prompt insulin zinc (Semilente) Examples of intermediate-acting insulins (peak 4–10 hours) are: Isophane insulin, neutral protamine Hagedorn (NPH) (Humulin N, Novolin N)
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Insulin glulisine, sold under the brand name Apidra among others, is a rapid-acting modified form of medical insulin used for the treatment of diabetes. It differs from human insulin in that the amino acid asparagine at position B3 is replaced by lysine and the lysine in position B29 is replaced by glutamic acid . [ 2 ]
In a previous review it was unclear if there is a difference in hypoglycemia, as there was not enough data to determine any differences with respect to long term outcomes, [15] however a more recent Cochrane systematic review did not find clinically significant difference when comparing insulin glargine to NPH insulin, insulin detemir or ...
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