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  2. Monoamine oxidase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Monoamine_oxidase_inhibitor

    Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They are best known as effective antidepressants , especially for treatment-resistant depression and atypical depression . [ 1 ]

  3. Monoamine oxidase A - Wikipedia

    en.wikipedia.org/wiki/Monoamine_oxidase_A

    Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. [ 5 ] [ 6 ] This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines , such as norepinephrine , serotonin and tyramine .

  4. Category:Reversible inhibitors of MAO-A - Wikipedia

    en.wikipedia.org/wiki/Category:Reversible...

    Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Pages for logged out editors learn more

  5. Harmala alkaloid - Wikipedia

    en.wikipedia.org/wiki/Harmala_alkaloid

    Harmaline and harmine fluorescence under ultraviolet light.These three extractions indicate that the middle one has a higher concentration of the two compounds. As mentioned above, some harmala alkaloids can be used as a monoamine oxidase inhibitor (MAOI) to facilitate the ingestion of dimethyltryptamine (DMT) and other tryptamines; while not generally used as a hallucinogen alone, there are ...

  6. Monoamine oxidase - Wikipedia

    en.wikipedia.org/wiki/Monoamine_oxidase

    Monoamine oxidases (MAO) (EC 1.4.3.4) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. [ 1 ] [ 2 ] They are found bound to the outer membrane of mitochondria in most cell types of the body.

  7. Moclobemide - Wikipedia

    en.wikipedia.org/wiki/Moclobemide

    Although it has been estimated that a single 300 mg dose of moclobemide inhibits 80% of monoamine oxidase-A (MAO-A) and 20-30% of MAO-B, [100] studies evaluating brain occupancy of MAO-A enzymes have shown dosages of 600 mg to only inhibit 74% of MAO-A enzymes [101] and dosages in the 900–1200 mg range to inhibit slightly less MAO-A than ...

  8. Harmaline - Wikipedia

    en.wikipedia.org/wiki/Harmaline

    Harmaline is a central nervous system stimulant and a "reversible inhibitor of MAO-A ()". [2] This means that the risk of a hypertensive crisis, a dangerous high blood pressure crisis from eating tyramine-rich foods such as cheese, is likely lower with harmaline than with irreversible MAOIs such as phenelzine.

  9. Harmine - Wikipedia

    en.wikipedia.org/wiki/Harmine

    Harmine is a beta-carboline and a harmala alkaloid.It occurs in a number of different plants, most notably the Syrian rue and Banisteriopsis caapi. [3] Harmine reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a Reversible inhibitor of monoamine oxidase A (RIMA).

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