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Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
Sildenafil can still be used to treat hypertension, but today, the primary use of this PDE5 inhibitor is to remedy ED. Other first-line treatment options for blood pressure and heart disease are ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Sildenafil is most commonly prescribed to be taken one time per day in doses between 25 and 100 mg for ED. Your healthcare provider will determine the best dosage for you based on a number of factors.
Remember that Viagra and sildenafil are the same. Sildenafil is the active ingredient in Viagra, meaning you’ll need to take the same precautions while drinking if you opt for generic sildenafil ...
The following pronunciation respelling key is used in some Wikipedia articles to respell the pronunciations of English words. It does not use special symbols or diacritics apart from the schwa (ə), which is used for the first sound in the word "about". See documentation for {} for examples and instructions on using the template.
Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.
The Merriam-Webster Online Dictionary suggests the first pronunciation. Similarly, this pronunciation markup guide will choose the most widely used form. NOTE: This guide is designed to be simple and easy to use. This can only be achieved by giving up scope and freedom from occasional ambiguity.