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SIRS is a serious condition related to systemic inflammation, organ dysfunction, and organ failure. It is a subset of cytokine storm, in which there is abnormal regulation of various cytokines. [6] SIRS is also closely related to sepsis, in which patients satisfy criteria for SIRS and have a suspected or proven infection. [2] [3] [4] [7]
A 2016 meta-analysis of transcranial direct current stimulation (tDCS) reported some efficacy of tDCS in the treatment of acute depressive disorder with moderate effect size, and low efficacy in treatment-resistant depression, and that use of 2 mA current strength over 20 minutes per day over a short time span can be considered safe. [166]
The quality of specific clinical formulations, and the quality of the general theoretical models used in those formulations, can be evaluated with criteria such as: [19] Clarity and parsimony : Is the model understandable and internally consistent , and are key concepts discrete, specific, and non-redundant?
Treatment guidelines from the National Institute of Health and Clinical Excellence [37] recommend against the use of SSRIs in this disorder. Those from the American Psychiatric Association note that SSRIs confer no advantage regarding weight gain, but that they may be used for the treatment of co-existing depression, anxiety, or OCD.
Treatment is typically intended to be brief, intense, and specific to the goals of the individual. [47] Goals are specific and measurable, focusing on single avoidance behaviors. Patients keep activity logs to monitor the feelings associated with different activities and therapists assign graded homework to help patients accomplish their goals.
Interpersonal therapy has been thought to be a good potential treatment for postpartum depression because it is short-term and focused on present life events and relationships. In one twelve week study using IPT, 100% of patients did not meet diagnostic criteria for postpartum depression by the end of the study.
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