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  2. Splenic sequestration crisis - Wikipedia

    en.wikipedia.org/wiki/Splenic_sequestration_crisis

    Up to 30% of these children may develop splenic sequestration crisis with a mortality rate of up to 15%. This crisis occurs when splenic vaso-occlusion causes a large percentage of total blood volume to become trapped within the spleen. Clinical signs include severe, rapid drop in hemoglobin leading to hypovolemic shock and death.

  3. Autosplenectomy - Wikipedia

    en.wikipedia.org/wiki/Autosplenectomy

    Increased deoxygenation causes sickling of red blood cells, which adhere to the spleen wall and splenic macrophages causing ischemia. [2] This ischemia can result in splenic sequestration, where large amounts of blood pool in the spleen but do not flow within vasculature. [11]

  4. Splenic infarction - Wikipedia

    en.wikipedia.org/wiki/Splenic_infarction

    Splenic infarction is a condition in which blood flow supply to the spleen is compromised, [1] leading to partial or complete infarction (tissue death due to oxygen shortage) in the organ. [2] Splenic infarction occurs when the splenic artery or one of its branches are occluded, for example by a blood clot .

  5. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    The spleen is especially prone to damage in SCD due to its role as a blood filter. A splenic sequestration crisis, also known as a spleen crisis, is a medical emergency that occurs when sickled red blood cells block the spleen's filter mechanism, causing the spleen to swell and fill with blood. The accumulation of red blood cells in the spleen ...

  6. Accessory spleen - Wikipedia

    en.wikipedia.org/wiki/Accessory_spleen

    The gonads may pick up some tissue from the spleen, and as they descend through the abdomen during development, they can produce either a continuous or a broken line of deposited splenic tissue. [12] Splenosis is a condition where foci of splenic tissue undergo autotransplantation, most often following physical trauma or splenectomy.

  7. Interventional radiology - Wikipedia

    en.wikipedia.org/wiki/Interventional_radiology

    High intensity focused ultrasound: Uses a machine that emits high frequency sound waves to kill cancer cells and provide relief for tumor-related pain, such as in the bone. Transarterial embolization (TAE)/ bland embolization : Injection of embolic material (microparticles, alcohol, glue) through a catheter into the arteries feeding a tumor to ...

  8. Felty's syndrome - Wikipedia

    en.wikipedia.org/wiki/Felty's_syndrome

    Splenomegaly is a condition of the spleen causing it to be enlarged. The splenic condition involving Felty syndrome is more specifically noted as inflammatory splenomegaly. The spleen is an important lymphatic organ that is involved in filtration of the blood by discarding old and damaged red blood cells as well as maintaining platelet levels ...

  9. Proton therapy - Wikipedia

    en.wikipedia.org/wiki/Proton_therapy

    In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer.The chief advantage of proton therapy over other types of external beam radiotherapy is that the dose of protons is deposited over a narrow range of depth; hence in minimal entry, exit, or scattered radiation dose to healthy ...

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