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The human protein is also frequently referred to as HER2 (human epidermal growth factor receptor 2) or CD340 (cluster of differentiation 340). [5] [6] [7]
In 1986 Axel Ullrich, a German scientist working at Genentech, first discovered the Her-2 protein and gave a conference about it in which Slamon was present.Afterwards Slamon proposed to work together, since he suspected that a mutation in Her-2 might cause cancer, eventually they found a kind of aggressive breast cancer with a mutation in the gene responsible for the Her-2 protein and started ...
Teleplay writer Vivienne Radkoff had the story for about seven years before it was completed. It is an adaptation of Robert Bazell's book HER-2: The Making of Herceptin, a Revolutionary Treatment for Breast Cancer. The film was the first mainstream feature film to be scored as a solo project by composer Halli Cauthery.
The AOL.com video experience serves up the best video content from AOL and around the web, curating informative and entertaining snackable videos.
In March 2010 YouTube began free streaming of certain content, including 60 cricket matches of the Indian Premier League. According to YouTube, this was the first worldwide free online broadcast of a major sporting event.
America Unearthed was an American entertainment television series and the first original series to air on the A&E Networks channel H2. [2] The show premiered on December 21, 2012, and was produced by Committee Films of Minneapolis, Minnesota. [ 3 ]
A study done on mice in early 2009 has indicated that when neuregulin-1\ErbB signalling is disrupted, the dendritic spines of neurons grow but do not fully form. This produced no immediate noticeable changes to brain development, but in adults there was a reduction of dendritic spines on neurons.
The full HERC2 gene is located at 15q13, encoded by 93 exons and its transcription is under the control of a CpG rich promoter.This region on chromosome 15 is susceptible to breaks during chromosomal rearrangement and there are at least 12 partial duplicates of HERC2 between 15q11–15q13.