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  2. My Years of Leg Pain Turned Out to Be ALS: Why the ... - AOL

    www.aol.com/lifestyle/years-leg-pain-turned-als...

    Brooke Eby was diagnosed with ALS, or Lou Gehrig's disease, at 33 years old. It took four years for doctors to identify her condition; at the time, her primary symptom was a tightness in her calf ...

  3. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    While the disease does not cause pain directly, pain is a symptom experienced by most people with ALS caused by reduced mobility. [36] Symptoms of lower motor neuron degeneration include muscle weakness and atrophy, muscle cramps, and fleeting twitches of muscles that can be seen under the skin ( fasciculations ).

  4. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    Weakness can be symmetric or asymmetric, and it can occur in body parts that are distal, proximal, or both. According to Statland et al., there are three main weakness patterns that are seen in motor neuron diseases, which are: [6] [9] Asymmetric distal weakness without sensory loss (e.g. ALS, PLS, PMA, MMA)

  5. Category:Amyotrophic lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Category:Amyotrophic...

    ALS is characterized by stiff muscles, muscle twitching, and gradually worsening weakness due to muscles decreasing in size. It may begin with weakness in the arms or legs, or with difficulty speaking or swallowing. About half of the people affected develop at least mild difficulties with thinking and behavior and most people experience pain.

  6. What is ALS? Oak Ridge Boys member Joe Bonsall died from ...

    www.aol.com/als-oak-ridge-boys-member-164302660.html

    ALS can manifest in people differently, but it usually starts with weakness that spreads or gets worse over time, according to the Mayo Clinic. Here are some of the symptoms of this fatal disease.

  7. Denervation - Wikipedia

    en.wikipedia.org/wiki/Denervation

    Following an acute poliovirus infection, symptoms such as fatigue, asthenia, and pain are believed to be linked to muscle denervation. [9] Much like post-polio syndrome, ALS also has similar symptoms of motor neurodegeneration leading to general weakness and, in some cases, paralysis. The type of symptoms experienced can depend on which areas ...

  8. Primary lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Primary_lateral_sclerosis

    Primary lateral sclerosis (PLS) usually presents with gradual-onset, progressive, lower-extremity stiffness and pain due to muscle spasticity. Onset is often asymmetrical. [ 2 ] Although the muscles do not appear to atrophy as in ALS (at least initially), the disabling aspect of PLS is muscle spasticity and cramping, and intense pain when those ...

  9. Multifocal motor neuropathy - Wikipedia

    en.wikipedia.org/wiki/Multifocal_motor_neuropathy

    Multifocal motor neuropathy (MMN) is a progressively worsening condition where muscles in the extremities gradually weaken.The disorder, a pure motor neuropathy syndrome, is sometimes mistaken for amyotrophic lateral sclerosis (ALS) because of the similarity in the clinical picture, especially if muscle fasciculations are present.

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