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  2. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    ALS is the most common motor neuron disease in adults and the third most common neurodegenerative disease [60] after Alzheimer's disease and Parkinson's disease. [119] Worldwide the number of people who develop ALS yearly is estimated to be 1.9 people per 100,000 per year, while the number of people who have ALS at any given time is estimated ...

  3. Riluzole - Wikipedia

    en.wikipedia.org/wiki/Riluzole

    Riluzole is a medication used to treat amyotrophic lateral sclerosis (ALS) and other motor neuron diseases. Riluzole delays the onset of ventilator-dependence or tracheostomy in some people and may increase survival by two to three months. [5] Riluzole is available in tablet and liquid form.

  4. What is ALS? Oak Ridge Boys member Joe Bonsall died from ...

    www.aol.com/als-oak-ridge-boys-member-164302660.html

    ALS can manifest in people differently, but it usually starts with weakness that spreads or gets worse over time, according to the Mayo Clinic. Here are some of the symptoms of this fatal disease.

  5. Edaravone - Wikipedia

    en.wikipedia.org/wiki/Edaravone

    In May 2017, I.V. edaravone was approved by the FDA to treat people with amyotrophic lateral sclerosis (ALS) in the United States. [13] The FDA approval was conditioned on Mitsubishi Tanabe completing several additional studies to clarify the risks of cancer and liver disease, among other effects of the medication. [14] [15]

  6. How to help a Sheboygan man as he battles ALS and ... - AOL

    www.aol.com/help-sheboygan-man-battles-als...

    According to Centers for Disease Control and Prevention data from 2018, about 30,000 people are living with ALS at any given time. The disease breaks down brain and spinal cord nerve cells, and ...

  7. Clene's ALS drug shows reduction in disease indicator levels ...

    www.aol.com/news/clenes-als-drug-shows-reduction...

    In April, the U.S. Food and Drug Administration granted accelerated approval for Biogen's ALS drug based on data that showed it reduced the protein levels. Clene's ALS drug shows reduction in ...

  8. Tofersen - Wikipedia

    en.wikipedia.org/wiki/Tofersen

    Tofersen was developed by Ionis Pharmaceuticals and was licensed to, and co-developed by, Biogen. [7] [8]The effectiveness of tofersen was evaluated in a 28-week, randomized, double-blind, placebo-controlled clinical study in 147 participants with weakness attributable to amyotrophic lateral sclerosis and a superoxide dismutase 1 (SOD-1) mutation confirmed by a central laboratory. [2]

  9. Estrogen and neurodegenerative diseases - Wikipedia

    en.wikipedia.org/wiki/Estrogen_and...

    Estrogen also plays very important role in animal metabolism balance. These unexpected diseases hindered estrogen to get involved in neurodegenerative disease therapy. So, when applying estrogen-like drugs to relieve neurodegenerative diseases, the concentration should be restrictly controlled to avoid these side effects. [citation needed]